Obesity and related consequences to ageing
| Autor: | Magdalena Jura, Leslie P. Kozak |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Gerontology Aging medicine.medical_specialty 030209 endocrinology & metabolism Disease Global Health Article 03 medical and health sciences Life Expectancy 0302 clinical medicine Risk Factors Prevalence Global health Humans Medicine Obesity Abdominal obesity Aged business.industry Public health General Medicine medicine.disease 030104 developmental biology Ageing Body Composition Life expectancy Insulin Resistance Geriatrics and Gerontology medicine.symptom Metabolic syndrome business |
| Zdroj: | AGE. 38 |
| ISSN: | 1574-4647 0161-9152 |
| DOI: | 10.1007/s11357-016-9884-3 |
| Popis: | Obesity has become a major public health problem. Given the current increase in life expectancy, the prevalence of obesity also raises steadily among older age groups. The increase in life expectancy is often accompanied with additional years of susceptibility to chronic ill health associated with obesity in the elderly. Both obesity and ageing are conditions leading to serious health problems and increased risk for disease and death. Ageing is associated with an increase in abdominal obesity, a major contributor to insulin resistance and the metabolic syndrome. Obesity in the elderly is thus a serious concern and comprehension of the key mechanisms of ageing and age-related diseases has become a necessary matter. Here, we aimed to identify similarities underlying mechanisms related to both obesity and ageing. We bring together evidence that age-related changes in body fat distribution and metabolism might be key factors of a vicious cycle that can accelerate the ageing process and onset of age-related diseases. |
| Databáze: | OpenAIRE |
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