An electron microscopic study of Schistosoma mansoni migration through mouse tissue: ultrastructure of the gut during the hepatoportal phase of migration
| Autor: | F. Pezzlo, J.I. Bruce, J.E. McCarty, Y. Yajima |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Pathology
medicine.medical_specialty Erythrocytes Time Factors Liver Diseases Parasitic Immunology Lumen (anatomy) Mice Inbred Strains Biology Cytoplasmic Granules Microtubules law.invention Mice Esophagus law Blood plasma medicine Methods Morphogenesis Parasite hosting Animals Schistosomiasis Cecum Biomphalaria Muscles Cell Membrane General Medicine Anatomy Schistosoma mansoni biology.organism_classification Red blood cell Microscopy Electron Infectious Diseases medicine.anatomical_structure Liver Larva Ultrastructure Parasitology Electron microscope Digestive System |
| Zdroj: | Experimental parasitology. 30(2) |
| ISSN: | 0014-4894 |
| Popis: | The migration of Schistosoma mansoni in mouse liver was studied with the aid of the electron microscope. The parasite was found within the central veins surrounded by host circulating blood cells. There was a mild inflammatory reaction in the bordering liver tissue. At this stage of development, the anatomy of the migrating larva was transformed by the appearance of a large central tube with a patent lumen representing the alimentary tract. The tube bifurcated caudally and formed two lateral ceca. The fine structure and contents of the alimentary tract were studied. The alimentary tract was divided into three major segments. The villous lining and muscular coats of each segment were appropriately adapted to the specific roles of ingestion, digestion, or egestion. The alimentary tract contained host red cells in various stages of dissolution, other cellular fragments, presumably derived from the host, and a granular amorphous material similar in density to host plasma. In the initial esophageal segment the luminal inclusions were relatively intact and easily identifiable. In the postesophageal segment and ceca the contents were transformed into electron-dense irregularly shaped granules. The appearance of these granules was similar to the hemoglobin-derived pigments described by other investigators. |
| Databáze: | OpenAIRE |
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