Zika virus infection in the genital tract of non-pregnant females: a systematic review
| Autor: | Raquel P. Souza, Edilson Damke, Marcia Edilaine Lopes Consolaro, Tamy Tuani Suehiro, Fabrício Morelli, Taís Elisângela da Cruz, Gabrielle Marconi Zago Ferreira Damke, Vânia Ramos Sela da Silva |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
030231 tropical medicine RC955-962 MEDLINE Review Zika virus 03 medical and health sciences 0302 clinical medicine Arctic medicine. Tropical medicine medicine Humans Sex organ Prospective cohort study Cervix biology Obstetrics business.industry Zika Virus Infection Genital tract Genitalia Female biology.organism_classification Non pregnant medicine.anatomical_structure Non-pregnant Vagina Female business Genital Diseases Female |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo, Volume: 62, Article number: e16, Published: 02 MAR 2020 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e16 Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e16 Revista do Instituto de Medicina Tropical de São Paulo Instituto de Medicina Tropical (IMT) instacron:IMT Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020) |
| ISSN: | 1678-9946 0036-4665 |
| Popis: | This review provides a general overview on the positivity and persistence of Zika virus (ZIKV) in female genital tract (FGT) of non-pregnant women and animals, as well as in cell cultures, and its influence on FGT health. We performed a systematic review based on the PRISMA statement to identify studies focused on “Zika virus” and “non-pregnant female” in PubMed, Embase, Scopus Scholar and Web of Knowledge databases of full-text papers and abstracts published in English, with no restrictions regarding the initial date of publication, up to August 2019. Our search terms yielded 625 records, that were 108 after removal of duplicates, leaving 517 items for title and abstract reviews. Of these, 475 did not meet the inclusion criteria, leaving 42 records for full-text review and resulting in the exclusion of 6 additional records. The remaining 36 met our inclusion criteria. Variations were observed regarding the presence and persistence of ZIKV in lower and upper genital samples. However, the FGT was the place in which ZIKV RNA has been detected, sometimes for relatively long periods, even after the clearance from blood and urine. In addition to the vagina and cervix, the endometrium, uterus and ovary (oocytes and follicles) could also be involved in persistent ZIKV infections. Further prospective studies are needed to assess the effect of ZIKV on FGT health. |
| Databáze: | OpenAIRE |
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