The effects of increased osmotic pressure on focal contacts and microfilament bundles of cultured fibroblasts
| Autor: | L.A. Lyass, T.M. Svitkina, Ju.M. Vasiliev |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Morphology (linguistics)
Cell Biology Microfilament Microtubules chemistry.chemical_compound Mice Cell Movement Osmotic Pressure medicine Cell Adhesion Osmotic pressure Animals Sorbitol Incubation Cells Cultured Cytoskeleton Cell Membrane Cell Biology Fibroblasts Cell biology Fibronectins Microscopy Electron medicine.anatomical_structure chemistry Cytoplasm Tonicity |
| Zdroj: | Experimental cell research. 141(2) |
| ISSN: | 0014-4827 |
| Popis: | Incubation of normal substrate-spread mouse fibroblasts in hypertonic medium containing 0.25 M sorbitol leads first to partial shrinkage of cytoplasm, but later the cells restore the normal flattened cell shape. However, these sorbitol-incubated cells, in contrast to control cells, had no discrete bundles of microfilaments and considerably a diminished number of focal cell-substrate contacts. Thus, by incubation with sorbitol, distribution of actin microfilaments and morphology of cell-substrate contacts can be switched from one pattern to another without concomitant changes of the cell shapes. |
| Databáze: | OpenAIRE |
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