Vitamin D in dysphagic patients who have undergone endoscopic gastrostomy for long-term enteral feeding
| Autor: | Carla Adriana Santos, Gonçalo Nunes, Ana Teresa Barata, Jorge Fonseca |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine Time Factors medicine.medical_treatment Gastroenterology Enteral administration Body Mass Index chemistry.chemical_compound 0302 clinical medicine Risk Factors Prevalence Medicine Prospective Studies Vitamin D Aged 80 and over Gastrostomy biology Transferrin Vitamins Dysphagia Middle Aged GEP Head and Neck Neoplasms Nutrición Female Adult Vitamin medicine.medical_specialty Vitamina D Serum albumin Disfagia 030209 endocrinology & metabolism Protein-Energy Malnutrition vitamin D deficiency Young Adult 03 medical and health sciences Enteral Nutrition Internal medicine Vitamin D and neurology Humans Serum Albumin Aged Nutrition 030109 nutrition & dietetics Hepatology business.industry Albumin Vitamin D Deficiency medicine.disease PEG Malnutrition chemistry biology.protein Deglutition Disorders business |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| Popis: | Objective Vitamin D plays a major role in biological processes. Its deficiency is associated with increased morbidity and mortality. Patients who have undergone endoscopic gastrostomy (PEG) present with protein-energy malnutrition, and may be at risk for Vitamin D deficiency, due to their age, less sunlight exposure and lower dietary intake. We aimed to determine the prevalence of hypovitaminosis D in PEG-patients, its change under PEG-feeding, and its relationship with serum proteins and risk factors for Vitamin D deficiency. Methods This was a prospective observational study, over 4 weeks, after gastrostomy. Data were collected at the initial PEG procedure (T0), and after 4 weeks (T1). Initial evaluation included age, gender, underlying disorder, NRS-2002, BMI, serum albumin, transferrin and Vitamin D. At T1 we assessed Vit. D, albumin, and transferrin. Vitamin D was performed with Electrochemiluminescence through Elecsys 2010 assay. Patients were fed with blended homemade meals. Results 200 patients (118 males), 22–92 years of age, were studied. There were initial low values for Vit. D (181), albumin (96), transferrin (121), and BMI (124). A correlation was found between Vit. D and serum albumin (r = 0.49, p = 0.005) but not with transferrin (r = 0.26, p = 0.195). At T1 the subgroup who had Vit. D levels assessed (n = 48) was part of the initial study group maintained low levels of Vitamin D despite nutritional intervention. Conclusion We recommend systematic Vitamin D supplementation of PEG fed patients using homemade meals or at least screening for hypovitaminosis D as a routine part of their care. |
| Databáze: | OpenAIRE |
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