Diagnostic performance of magnifying blue laser imaging versus magnifying narrow-band imaging for identifying the depth of invasion of superficial esophageal squamous cell carcinoma
| Autor: | Tomohiro Ueda, Ken Inoue, Naoto Iwai, Takahiro Nakano, Kazuhiko Uchiyama, Osamu Dohi, Takuma Yoshida, Hiroaki Kitae, Tomohisa Takagi, Takeshi Ishikawa, Kazuhiro Kamada, Hideyuki Konishi, Shinya Matsumura, Yuka Azuma, Ayako Nishimura, Yuji Naito, Naoki Mizuno, Naohisa Yoshida, Mitsuo Kishimoto, Ryohei Hirose, Tsugitaka Ishida, Shun Takayama, Yoshito Itoh |
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| Rok vydání: | 2020 |
| Předmět: |
Muscularis mucosae
Esophageal Neoplasms Esophageal squamous cell carcinoma Narrow Band Imaging 03 medical and health sciences 0302 clinical medicine Japan Submucosa Humans Medicine Endoscopic resection Retrospective Studies Lamina propria Narrow-band imaging business.industry Lasers Gastroenterology General Medicine Endoscopic submucosal dissection medicine.anatomical_structure Head and Neck Neoplasms Depth of invasion 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Esophageal Squamous Cell Carcinoma Esophagoscopy Nuclear medicine business |
| Zdroj: | Diseases of the Esophagus. 34 |
| ISSN: | 1442-2050 1120-8694 |
| Popis: | Summary Identifying the depth of invasion (DOI) of superficial esophageal squamous cell carcinoma (SESCC) is crucial to determine the indication for endoscopic resection. This retrospective, single-center study aimed to evaluate the diagnostic efficacy of magnifying blue laser imaging (M-BLI) compared with white-light imaging (WLI) or magnifying narrow-band imaging (M-NBI) for identifying the DOI of SESCC. A total of 160 consecutive patients with SESCCs who underwent endoscopic submucosal dissection were enrolled in this study. Still images of the lesion were obtained using WLI, M-BLI and M-NBI prior to endoscopic submucosal dissection. Three endoscopists retrospectively evaluated the DOI using WLI according to non-magnifying findings and using M-BLI and M-NBI images according to the magnifying endoscopic classification of the Japan Esophageal Society. The diagnostic accuracy of each modality was compared using the chi-square test. The DOIs in 160 SESCCs evaluated pathologically were as follows: invasion to the epithelium or lamina propria mucosa in 130, invasion to the lamina muscularis mucosa or submucosa to a depth ≤ 200 μm in 18, and invasion to the submucosa to a depth > 200 μm in 12. The overall diagnostic accuracy rates of WLI, M-BLI, M-NBI, WLI with M-BLI (WLI + M-BLI), and WLI with M-NBI (WLI + M-NBI) were 86.9, 91.2, 90.6, 95.6 and 94.4%, respectively. Significant differences were found between WLI and WLI + M-BLI or WLI + M-NBI (P = 0.006 and P = 0.021, respectively). The concordance of intrapapillary capillary loops between M-BLI and M-NBI was 91.2%. The kappa coefficients for interobserver variability of the three endoscopists for M-BLI and M-NBI were 0.728/0.649/0.792 and 0.729/0.666/0.791, respectively, while those for intraobserver variability were 0.919/0.746/0.778 and 0.736/0.720/0.745, respectively. Similar to M-NBI, M-BLI was useful in predicting the DOI of SESCCs. |
| Databáze: | OpenAIRE |
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