Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Parkinson's disease
| Autor: | Joaquín Arenas, José Antonio Navarro, A. Tallón-Barranco, M. Ortí-Pareja, F. de Bustos, F J Jiménez-Jiménez, Julián Benito-León, JoséAntonio Molina, T. Gasallo, R. Enríquez-de-Salamanca |
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| Rok vydání: | 1997 |
| Předmět: |
Male
Vitamin medicine.medical_specialty Parkinson's disease Antioxidant medicine.medical_treatment Antiparkinson Agents Central nervous system disease chemistry.chemical_compound Cerebrospinal fluid Degenerative disease Reference Values Internal medicine Humans Vitamin E Medicine Chromatography High Pressure Liquid Biological Psychiatry Aged business.industry Parkinson Disease Middle Aged medicine.disease Psychiatry and Mental health Endocrinology Neurology chemistry Female Neurology (clinical) business alpha-Tocopherol |
| Zdroj: | Journal of Neural Transmission. 104:1287-1293 |
| ISSN: | 1435-1463 0300-9564 |
| DOI: | 10.1007/bf01294729 |
| Popis: | We compared CSF and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 34 patients with Parkinson's disease (PD) and 47 controls. CSF and serum vitamin E levels were correlate. The mean CSF and serum vitamin E levels, and the CSF/serum ratio of PD patients did not differ significantly between the groups. There was no influence of antiparkinsonian therapy on CSF vitamin E levels. CSF vitamin E levels did not correlate with age, age at onset, duration of the disease, scores of the Unified Parkinson Disease Rating Scale of the Hoehn and Yahr staging in the PD group. These results suggest that CSF vitamin E concentrations are unrelated with the risk for PD. |
| Databáze: | OpenAIRE |
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