Endothelial function in response to exercise in the cold in patients with coronary artery disease
| Autor: | Juha S. Perkiömäki, Tiina M. Ikäheimo, Matti Mäntysaari, Rasmus I. P. Valtonen, Antti M. Kiviniemi, Jouni J. K. Jaakkola, Craig G. Crandall, Heidi E. Hintsala, Arto J. Hautala, Niilo R.I. Ryti |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Physiology Physical exercise Coronary Artery Disease 030204 cardiovascular system & hematology Coronary artery disease 03 medical and health sciences Hyperaemia 0302 clinical medicine Environmental temperature Physiology (medical) medicine.artery Internal medicine medicine Aerobic exercise Humans In patient cardiovascular diseases Brachial artery Exercise business.industry 030229 sport sciences General Medicine Middle Aged medicine.disease Cold Temperature FMD protocol Cardiology Endothelium Vascular medicine.symptom business |
| Zdroj: | Clinical physiology and functional imagingREFERENCES. 40(4) |
| ISSN: | 1475-097X |
| Popis: | BACKGROUND Regular long-term physical exercise has favourable effects on endothelial function in patients with coronary artery disease (CAD). However, the effects of an acute exercise bout in the cold on endothelial function are not known. METHODS At first, the effects of moderate-intensity aerobic lower-body exercise were assessed in CAD patients (n = 16) in a neutral [+22°C] and cold [-15°C] environment. Secondly, responses to static and dynamic upper-body exercise in a neutral [+22°C] and cold [-15°C] environment were investigated in CAD patients (n = 15). All experiments were performed in a random order. Endothelial function was measured by flow-mediated dilation (FMD) of the brachial artery in response to reactive hyperaemia, before and after the exposures in a neutral environment. RESULTS No significant temperature*exercise*condition (pre-post) interaction was observed in FMD% when comparing rest versus aerobic exercise or static versus dynamic upper-body exercise. Relative reactive hyperaemia during FMD protocol, measured by changes in shear rate, was elevated after rest compared to aerobic exercise (p = .001) and after static compared to dynamic upper-body exercise (p |
| Databáze: | OpenAIRE |
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