Lipid peroxidation in homocysteinaemia
| Autor: | Ad M. Stadhouders, D. P. E. Engelen, R. C. A. Sengers, R.A. de Abreu, M. T. W. B. TePoele-Pothoff, J. M. F. Trijbels, Henk J. Blom, Godfried H.J. Boers |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
medicine.medical_specialty Homocysteine Cystathionine beta-Synthase Homocystinuria Lipid peroxidation Pathogenesis chemistry.chemical_compound Internal medicine Malondialdehyde Genetics Medicine Humans Genetics (clinical) biology business.industry Vascular disease Homozygote Heterozygote advantage medicine.disease Cystathionine beta synthase Endocrinology Spectrometry Fluorescence chemistry biology.protein Lipid Peroxidation business |
| Zdroj: | Journal of inherited metabolic disease. 15(3) |
| ISSN: | 0141-8955 |
| Popis: | Homocysteinaemia due to cystathione synthase deficiency (CSD: McKusick 236200) is a rare autosomal recessive inborn error of methionine metabolism. The most life-threatening complications caused by CSD are thromboembolism and vascular abnormalities. Boers et al (1985) provided evidence that even mild homocysteinaemia, as seen in heterozygote CSD patients, is predisposing for development of premature peripheral and cerebral occlusive arterial disease |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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