Oestrogen Therapy in Turner's Syndrome
Autor: | K W Kastrup |
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Rok vydání: | 2008 |
Předmět: |
endocrine system
medicine.medical_specialty Adolescent Turner Syndrome Estrogen therapy Internal medicine polycyclic compounds Humans Medicine Child skin and connective tissue diseases Volume concentration Bone Development Estradiol business.industry Final height General Medicine Turner's syndrome Somatomedin Body Height Growth hormone secretion Endocrinology Pediatrics Perinatology and Child Health Bone maturation Female business hormones hormone substitutes and hormone antagonists |
Zdroj: | Acta Paediatrica. 77:43-46 |
ISSN: | 0803-5253 |
Popis: | Oestradiol stimulates growth and development in Turner's syndrome. Previous results with low-dose oestradiol on growth rate are reviewed. The effect of oestradiol in low concentrations on somatomedin generation, GH secretion and directly on osseous tissue, may explain the growth response. The observations presented here of 35 girls treated with 17-beta-oestradiol demonstrated a definite increase in growth rate in the first year of therapy. Bone maturation was accelerated, but a reduction in final height was not found. |
Databáze: | OpenAIRE |
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