De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes

Autor: Xianran Li, Marcela K. Tello-Ruiz, Doreen Ware, Qiuhan Jiang, Robert J. Schmitz, Margaret R. Woodhouse, Carson M. Andorf, Dong Won Kim, Zhenyuan Lu, R. Kelly Dawe, Ethalinda K. S. Cannon, Arun S. Seetharam, Kevin Fengler, Ksenia V. Krasileva, David Kudrna, Amanda M. Gilbert, Jeffrey Ross-Ibarra, Rebecca D. Piri, Alexandre P. Marand, Yinjie Qiu, Nancy Manchanda, Christine H. O’Connor, Jonathan I. Gent, Silas Tittes, Michael Syring, Sharon Wei, Rafael Della Coletta, Candice N. Hirsch, Shujun Ou, Matthew B. Hufford, Jianing Liu, Na Wang, David E. Hufnagel, Samantha J. Snodgrass, Erin Baggs, Kapeel Chougule, Tingting Guo, Jianming Yu, Andrew Olson, John L. Portwood, Bo Wang, Sarah Pedersen, Yibing Zeng, Asher I. Hudson, William A. Ricci, Victor Llaca
Rok vydání: 2021
Předmět:
0106 biological sciences
Multifactorial Inheritance
Genotype
General Science & Technology
Population
Centromere
Sequence assembly
Computational biology
Biology
Regulatory Sequences
Nucleic Acid

Genes
Plant

01 natural sciences
Genome
Polymorphism
Single Nucleotide

Zea mays
Chromosomes
Plant

Article
Structural variation
03 medical and health sciences
Genetic variation
Nested association mapping
education
030304 developmental biology
Disease Resistance
Plant Diseases
2. Zero hunger
Comparative genomics
0303 health sciences
education.field_of_study
Multidisciplinary
Whole Genome Sequencing
Chromosome Mapping
Genetic Variation
High-Throughput Nucleotide Sequencing
Molecular Sequence Annotation
Genome project
Sequence Analysis
DNA

DNA Methylation
Tetraploidy
Phenotype
Transcriptome
Genome
Plant

010606 plant biology & botany
Zdroj: Science
Science (New York, N.Y.), vol 373, iss 6555
ISSN: 1095-9203
Popis: An a-maize-ing set of genomes Maize is an important crop cultivated worldwide. As maize spread across the world, selection for local environments resulted in variation, but the impact on differences between the genome has not been quantified. By producing high-quality genomic sequences of the 26 lines used in the maize nested association mapping panel, Hufford et al . map important traits and demonstrate the diversity of maize. Examining RNA and methylation of genes across accessions, the authors identified a core set of maize genes. Beyond this core set, comparative analysis across lines identified high levels of variation in the total set of genes, the maize pan-genome. The value of this resource was further exemplified by mapping quantitative traits of interest, including those related to pathogen resistance. —LMZ
Databáze: OpenAIRE
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