Respiratory symptoms and long-term cardiovascular mortality
| Autor: | Vidar Søyseth, Amund Gulsvik, Aage Andersen, Tor Haldorsen, Anne Frostad |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Population Myocardial Ischemia Cohort Studies Risk Factors Surveys and Questionnaires Internal medicine Epidemiology medicine Humans Respiratory symptoms cardiovascular diseases Mortality education Stroke Aged Proportional Hazards Models Asthma education.field_of_study Ischaemic heart disease Norway Proportional hazards model business.industry Smoking Hazard ratio Absolute risk reduction Middle Aged Respiration Disorders medicine.disease Data Interpretation Statistical Physical therapy Female Cohort study business |
| Zdroj: | Respiratory Medicine. 101:2289-2296 |
| ISSN: | 0954-6111 |
| Popis: | Summary Background Our aim was to investigate the association between respiratory symptoms and mortality from ischaemic heart disease (IHD) and stroke in a population during 30 years follow-up. Methods In 1972, 19 998 persons aged 15–70 years, living in Oslo, were selected for a respiratory survey (response 89%). Respiratory symptoms were divided into four groups and given a score. The association between respiratory symptoms and mortality from IHD and stroke were investigated separately for men and women, with adjustment for age, occupational exposure to air pollution and smoking habits. Results IHD accounted for 1572 and stroke for 653 of all deaths. The adjusted hazard ratio (HR) for mortality from IHD in men varied from 1.3 (95% confidence interval, 1.1–1.5) to 3.0 (2.3–3.8) and in women from 1.2 (1.0–1.5) to 1.9 (1.4–2.5) for cough symptoms and severe dyspnoea, respectively. Symptom score predicted death from IHD, in a dose–response manner. The HR for mortality from stroke varied from 1.0 to 2.3 in men and from 1.1 to 1.5 in women for the symptom groups, but was significant only among men reporting severe dyspnoea and among women reporting moderate dyspnoea. For all respiratory symptoms, the excess risk for cardiovascular mortality decreased during follow-up, but IHD-mortality was still significantly increased the last decade. Conclusion We found a significant, positive association between respiratory symptoms and 30-year mortality from IHD. The positive association was weaker between respiratory symptoms and long-term mortality from stroke. |
| Databáze: | OpenAIRE |
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