Comparison of Cytomorphometry and Early Cell Response of Human Gingival Fibroblast (HGFs) between Zirconium and New Zirconia-Reinforced Lithium Silicate Ceramics (ZLS)
| Autor: | María-Ángeles Serrera-Figallo, Daniel Torres-Lagares, José-Luis Gutiérrez-Pérez, Irene Luna-Oliva, María Rizo-Gorrita |
|---|---|
| Přispěvatelé: | Universidad de Sevilla. Departamento de Estomatología |
| Rok vydání: | 2018 |
| Předmět: |
Ceramics
Scanning electron microscope gingival fibroblast Gingiva Computer-aided design Biocompatible Materials early cell spreading 02 engineering and technology Cell morphology law.invention lcsh:Chemistry Early cell proliferation 0302 clinical medicine Cell Movement law Materials Testing zirconia reinforced-lithium silicate ceramic (ZLS) Zirconia reinforced-lithium silicate ceramic CAD Cubic zirconia lcsh:QH301-705.5 Spectroscopy CAM Prostheses and Implants General Medicine 021001 nanoscience & nanotechnology Computer Science Applications Lithium 0210 nano-technology early cell proliferation Materials science Biocompatibility Surface Properties Energy-dispersive X-ray spectroscopy chemistry.chemical_element Article Catalysis Cell Line Inorganic Chemistry 03 medical and health sciences Confocal microscopy Early cell spreading Humans Gingival fibroblast Physical and Theoretical Chemistry ZLS Molecular Biology Cell Proliferation Zirconium Silicates computer-aided design/computer-aided manufacturing (CAD/CAM) materials Organic Chemistry Computer-aided manufacturing 030206 dentistry Fibroblasts lcsh:Biology (General) lcsh:QD1-999 chemistry Zirconia zirconia Biomedical engineering |
| Zdroj: | idUS. Depósito de Investigación de la Universidad de Sevilla instname International Journal of Molecular Sciences Volume 19 Issue 9 International Journal of Molecular Sciences, Vol 19, Iss 9, p 2718 (2018) |
| ISSN: | 1422-0067 |
| DOI: | 10.3390/ijms19092718 |
| Popis: | New zirconia-reinforced lithium silicate ceramics (ZLS) could be a viable alternative to zirconium (Y-TZP) in the manufacture of implantological abutments&mdash especially in aesthetic cases&mdash due to its good mechanical, optical, and biocompatibility properties. Although there are several studies on the ZLS mechanical properties, there are no studies regarding proliferation, spreading, or cytomorphometry. We designed the present study which compares the surface, cellular proliferation, and cellular morphology between Y-TZP (Vita YZ® T [Vita Zahnfabrik (Postfach, Germany)]) and ZLS (Celtra® Duo [Degudent (Hanau-Wolfgang, Germany)]). The surface characterization was performed with energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), and optical profilometry. Human gingival fibroblasts (HGFs) were subsequently cultured on both materials and early cellular response and cell morphology were compared through nuclear and cytoskeletal measurement parameters using confocal microscopy. The results showed greater proliferation and spreading on the surface of Y-TZP. This could indicate that Y-TZP continues to be a gold standard in terms of transgingival implant material: Nevertheless, more in vitro and in vivo research is necessary to confirm the results obtained in this study. |
| Databáze: | OpenAIRE |
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