Candidemia in the Neonatal Intensive Care Unit: A Retrospective, Observational Survey and Analysis of Literature Data
| Autor: | Osvalda De Giglio, Giuseppina Caggiano, O. Montagna, Nicola Laforgia, G Lovero, Giovanna Barbuti, Maria Teresa Montagna |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Pediatrics Neonatal intensive care unit Antifungal Agents Candida parapsilosis Article Subject 030106 microbiology lcsh:Medicine General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Risk Factors Intensive Care Units Neonatal Surveys and Questionnaires Epidemiology Candida albicans Medicine Humans General Immunology and Microbiology biology business.industry Incidence (epidemiology) lcsh:R Infant Newborn Candidemia Infant General Medicine biology.organism_classification Corpus albicans Europe Parenteral nutrition Italy Observational study Female business Research Article |
| Zdroj: | BioMed Research International, Vol 2017 (2017) BioMed Research International |
| ISSN: | 2314-6141 2314-6133 |
| Popis: | We evaluated the epidemiology ofCandidabloodstream infections in the neonatal intensive care unit (NICU) of an Italian university hospital during a 9-year period as a means of quantifying the burden of infection and identifying emerging trends. Clinical data were searched for in the microbiological laboratory database. For comparative purposes, we performed a review of NICU candidemia. Forty-one candidemia cases were reviewed (overall incidence, 3.0 per 100 admissions).Candida parapsilosis sensu stricto(58.5%) andC. albicans(34.1%) were the most common species recovered. A variable drift through years was observed; in 2015, 75% of the cases were caused by non-albicansspecies. The duration of NICU hospitalization of patients with non-albicanswas significantly longer than in those withC. albicans(median days, 10 versus 12). Patients with non-albicansspecies were more likely to have parenteral nutrition than those withC. albicans(96.3% versus 71.4%).Candida albicanswas the dominant species in Europe and America (median, 55% and 60%; resp.); non-albicansspecies predominate in Asia (75%). Significant geographic variation is evident among cases of candidemia in different parts of the world, recognizing the importance of epidemiological data to facilitate the treatment. |
| Databáze: | OpenAIRE |
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