Mass Production of Stem Cell-Derived Progeny in Bioreactors

Autor: Li Y, Sart S, Agathos SN
Rok vydání: 2018
DOI: 10.6084/m9.figshare.5765751.v1
Popis: Stem cells, including mesenchymal stem cells (MSCs) and pluripotentstem cells (PSCs), have shown great potential for variousbiomedical applications including drug discovery, disease modeling,and tissue engineering. Especially, the discovery ofinduced pluripotent stem cells (iPSCs) with similar characteristicsto embryonic stem cells (ESCs) opens a new era for stem cell researchand transplantations. Bioprocess engineering providesa platform to generate a controlled microenvironment that couldpotentially recreate a stem cell niche in view of promoting stemcell proliferation or lineage-specific differentiation.
Databáze: OpenAIRE
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