Application of Composite Hydrogels to Control Physical Properties in Tissue Engineering and Regenerative Medicine
| Autor: | Kaylee Meyers, Cassidy Sheffield, Emil Johnson, Rupak M. Rajachar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Tissue architecture Materials science Polymers and Plastics Composite number Normal tissue Bioengineering Nanotechnology 02 engineering and technology Review Regenerative medicine composites lcsh:Chemistry Biomaterials 03 medical and health sciences Composite hydrogels controlled physical properties lcsh:General. Including alchemy Tissue engineering lcsh:Inorganic chemistry lcsh:Science hydrogels Organic Chemistry 021001 nanoscience & nanotechnology lcsh:QD146-197 3. Good health 030104 developmental biology lcsh:QD1-999 tissue engineering Native tissue Self-healing hydrogels lcsh:Q 0210 nano-technology lcsh:QD1-65 |
| Zdroj: | Gels Gels, Vol 4, Iss 2, p 51 (2018) |
| ISSN: | 2310-2861 |
| Popis: | The development of biomaterials for the restoration of the normal tissue structure–function relationship in pathological conditions as well as acute and chronic injury is an area of intense investigation. More recently, the use of tailored or composite hydrogels for tissue engineering and regenerative medicine has sought to bridge the gap between natural tissues and applied biomaterials more clearly. By applying traditional concepts in engineering composites, these hydrogels represent hierarchical structured materials that translate more closely the key guiding principles required for improved recovery of tissue architecture and functional behavior, including physical, mass transport, and biological properties. For tissue-engineering scaffolds in general, and more specifically in composite hydrogel materials, each of these properties provide unique qualities that are essential for proper augmentation and repair following disease and injury. The broad focus of this review is on physical properties in particular, static and dynamic mechanical properties provided by composite hydrogel materials and their link to native tissue architecture and, ultimately, tissue-specific applications for composite hydrogels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|