Intraocular pressure and myopia progression in Chinese children: the Anyang Childhood Eye Study
Autor: | Gabriel Martin, Ningli Wang, Shi-Ming Li, Meng-Tian Kang, Rafael Iribarren, Shifei Wei, William K. Stell, He Li, Luo-Ru Liu |
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Rok vydání: | 2018 |
Předmět: |
Male
China medicine.medical_specialty Intraocular pressure Biometry genetic structures Spherical equivalent Refraction Ocular Cohort Studies Tonometry Ocular 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Asian People Ophthalmology Epidemiology Myopia medicine Humans Prospective Studies Child Intraocular Pressure Cycloplegic refractions business.industry eye diseases Sensory Systems Disease Progression 030221 ophthalmology & optometry Female sense organs business 030217 neurology & neurosurgery Follow-Up Studies Cohort study |
Zdroj: | British Journal of Ophthalmology. 103:349-354 |
ISSN: | 1468-2079 0007-1161 |
DOI: | 10.1136/bjophthalmol-2017-311831 |
Popis: | PurposeTo explore the relationship between intraocular pressure (IOP) at baseline and myopia progression in Chinese children from the Anyang Childhood Eye Study.DesignProspective school-based cohort study.MethodsA total of 1558 grade 7 students completed the entire 2-year study. Ocular biometry, cycloplegic refractions and pneumotonometry were performed. Three years of follow-up have been completed for the children aged 12 years. The refractive groups and the tertiles of IOP were assessed by analysis of variance, to look for differences in mean values of spherical equivalent and IOP, respectively.ResultsThe children’s mean baseline IOP was 15.87±3.42 mm Hg. Mean IOP was significantly higher in girls by 0.57 mm Hg (p=0.024). In the whole sample, there was a mean change in spherical equivalent of −1.05 D over 2 years. The baseline IOP was 15.69 mm Hg in those progressing 1 D or more vs 16.09 mm Hg for those progressing 1 D had mean IOP of 15.94 vs 16.42 mm Hg for those myopes progressing 1 D or less (p=0.024).ConclusionsIn this sample of Chinese children, myopia progression over 2 years was inversely related to IOP, suggesting that IOP had essentially no relationship with myopia progression in school children. The lower IOP in progressing myopic eyes may indicate more compliant sclerae. |
Databáze: | OpenAIRE |
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