Characterization of calcium phosphate layers grown on polycaprolactone for tissue engineering purposes
| Autor: | J. Suay Antón, J.L. Gómez Ribelles, Myriam Lebourg |
|---|---|
| Přispěvatelé: | Universitat Politècnica de València (UPV), Centro de Investigación Príncipe Felipe, Centro de Investigación Principe Felipe |
| Rok vydání: | 2010 |
| Předmět: |
Materials science
Simulated body fluid Fourier Transform Infrared Spectroscopy(D) chemistry.chemical_element 02 engineering and technology Calcium 010402 general chemistry 01 natural sciences X-ray diffraction(D) Apatite [SPI.MAT]Engineering Sciences [physics]/Materials Crystallinity chemistry.chemical_compound Ceramics(A) Composite material Magnesium ion Polymer(A) General Engineering 021001 nanoscience & nanotechnology 0104 chemical sciences chemistry Chemical engineering visual_art Polycaprolactone Ceramics and Composites visual_art.visual_art_medium Carbonate 0210 nano-technology Surface Treatment(B) Biomineralization |
| Zdroj: | Composites Science and Technology Composites Science and Technology, Elsevier, 2010, 70 (13), pp.1796. ⟨10.1016/j.compscitech.2010.07.017⟩ |
| ISSN: | 0266-3538 |
| Popis: | International audience; Composites fabricated by biomimetic mineral precipitation on polymeric substrates are of interest for tissue engineering. As biological properties of such mineral layers vary with slight changes in composition, a good physical characterization is necessary in order to study their biological activity. In this work polycaprolactone sheets were subjected to air plasma treatment followed by nucleation of calcium phosphate seeds to activate the growth of an apatite-like coating when immersing in simulated body fluid. Two compositions of the SBF were prepared, one of them highly carbonated and the other with no carbonate or magnesium ions. Immersion of PCL in the high carbonate composition produced a low-crystallinity apatite-like layer while the absence of carbonate and magnesium ions yielded a high crystallinity apatite with low Ca/P ratio that is likely partially hydrolyzed octacalciumphosphate (OCP). The morphology, crystal structure and composition of both types of coatings were characterised; osteoblast-like cell adhesion behaviour on different surfaces was observed by fluorescence and electron microscopy. |
| Databáze: | OpenAIRE |
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