Incorporating Bioaccessibility into Human Health Risk Assessment of Heavy Metals in Rice (Oryza sativa L.): A Probabilistic-Based Analysis
| Autor: | Qiang Zhang, Xuyin Yuan, Xiaowen Fu, Jizhou Li, Shuhai Guo, Junfeng Ji, Yinxian Song, Tianyuan Li |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_element
010501 environmental sciences Oryza Risk Assessment 01 natural sciences Human health 0404 agricultural biotechnology Metals Heavy Humans Soil Pollutants Health risk Arsenic 0105 earth and related environmental sciences Oryza sativa Health risk assessment biology Heavy metals 04 agricultural and veterinary sciences General Chemistry biology.organism_classification 040401 food science chemistry Environmental chemistry General Agricultural and Biological Sciences Risk assessment |
| Zdroj: | Journal of Agricultural and Food Chemistry. 66:5683-5690 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/acs.jafc.8b01525 |
| Popis: | A systematic investigation into total and bioaccessible heavy metal concentrations in rice grains harvested from heavy metal-contaminated regions was carried out to assess the potential health risk to local residents. Arsenic, Cr, Cu, Pb, and Zn concentrations were within acceptable levels while Cd and Ni concentrations appeared to be much higher than in other studies. The bioaccessibity of As, Cd, and Ni was high (>25%) and could be well predicted from their total concentrations. The noncarcinogenic risk posed by As and Cd was significant. The carcinogenic risk posed by all bioaccessible heavy metals at the fifth percentile was 10-fold higher than the acceptable level, and Cd and Ni were the major contributors. The contribution of each metal to the combined carcinogenic risk indicates that taking pertinent precautions for different types of cancer, aimed at individuals with different levels of exposure to heavy metals, will greatly reduce morbidity and mortality rates. |
| Databáze: | OpenAIRE |
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