Release of enkephalin-like immunoreactive material from isolated bovine chromaffin cells
| Autor: | E. Costa, S.M. Stine, H.-Y.T. Yang |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
endocrine system
medicine.medical_specialty Time Factors Enkephalin Potassium chemistry.chemical_element In Vitro Techniques Cellular and Molecular Neuroscience Internal medicine medicine Animals Cells Cultured Pharmacology Nicotinic Receptors Enkephalins Acetylcholine Endocrinology Biochemistry chemistry Adrenal Medulla Chromaffin System Cattle Endorphins medicine.drug |
| Zdroj: | Neuropharmacology. 19(7) |
| ISSN: | 0028-3908 |
| Popis: | The enkephalin-like immunoreactive material which is stored in primary cultures of bovine chromaffin cells is released spontaneously when these cells are transferred from the culture medium to the Krebs-Ringer buffer. Potassium (56 mM) and acetylcholine (10−4M) increase this rate of spontaneous release in a Ca2+ dependent fashion. Preliminary evidence indicates that nicotinic receptors are operative in mediating the release of enkephalin-like peptides elicited by acetylcholine. |
| Databáze: | OpenAIRE |
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