Infant dietary exposure to dioxin-like polychlorinated biphenyls (dlPCBs), polybrominated and mixed halogenated dibenzo-p-dioxins and furans (PBDD/Fs and PXDD/Fs) in milk samples of lactating mothers in Accra, Ghana
| Autor: | Eric J. Reiner, Sam Adu-Kumi, Gareth Rhys Jones, Karl J. Jobst, Edith Clarke, David Megson, Joseph A. Gardella, Pennante Bruce-Vanderpuije |
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| Rok vydání: | 2019 |
| Předmět: |
Environmental Engineering
Daily intake Health Toxicology and Mutagenesis 0208 environmental biotechnology Mothers 02 engineering and technology 010501 environmental sciences Body weight Dioxins 01 natural sciences Ghana World health Dietary Exposure Animal science Environmental Chemistry Medicine Animals Humans Lactation Furans 0105 earth and related environmental sciences Dietary exposure business.industry Dietary intake Public Health Environmental and Occupational Health Infant General Medicine General Chemistry Dibenzofurans Polychlorinated Pollution Polychlorinated Biphenyls 020801 environmental engineering Female business |
| Zdroj: | Chemosphere. 263 |
| ISSN: | 1879-1298 |
| Popis: | In this study, polybrominated and mixed halogenated dibenzo-p-dioxins and furans (PBDD/Fs and PXDD/Fs), and dioxin-like polychlorinated biphenyls (dlPCBs) were quantified in 24 human milk samples of first-time lactating mothers from Greater Accra region in Ghana. The aims of the study were to determine the concentrations and toxic equivalent concentrations of PBDD/F, PXDD/F and dlPCBs in human milk, and to estimate an infant's daily intake. The samples were analysed for 12 dioxin-like PCBs, 7 congeners of 2,3,7,8-polybrominated dibenzo-p-dioxins and furans (PBDD/Fs), and 7 congeners of 2,3,7,8-mixed halogenated dioxins and furans (PXDD/Fs, where X = Br/Cl). The mean concentrations in human milk ranged from 0.15 to 212.9 pg/g lipid for dlPCB congeners (mean TEQ: 1.67 pg WHO2005-TEQ/g lipid). Lesser concentrations for 2,3,7,8-PXDD/Fs (and PBDD/Fs congeners) ranged between |
| Databáze: | OpenAIRE |
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