Incidental Learning and Memory Deficits on a Computerized Symbol-Digit Modalities Test in Adults with HIV/AIDS
| Autor: | David J. Hardy, Charles H. Hinkin, Steven A. Castellon |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Memory Disorders medicine.medical_specialty Modalities business.industry General Neuroscience Human immunodeficiency virus (HIV) HIV Infections Symbol digit modalities test Neuropsychological Tests Audiology medicine.disease_cause medicine.disease Incidental learning Psychiatry and Mental health Clinical Psychology Acquired immunodeficiency syndrome (AIDS) Reaction Time Humans Learning Medicine Neurology (clinical) Cognitively impaired business Set (psychology) |
| Zdroj: | Journal of the International Neuropsychological Society. 27:389-395 |
| ISSN: | 1469-7661 1355-6177 |
| Popis: | Objective:Incidental learning and memory, as well as processing speed, were examined in human immunodeficiency virus (HIV)-positive adults and a seronegative control group.Methods:Participants completed a computerized Symbol-Digit Modalities Test (cSDMT) with two blocked conditions: a set of trials with the standard symbol–digit pairings and the second set with a rearranged symbol–digit pairings.Results:HIV-positive adults showed slower overall reaction time compared to the HIV-negative group. More importantly, the most cognitively impaired HIV-positive group showed no interference in the rearranged set of symbol–digit pairings from the standard pairings on the cSDMT.Conclusion:The relative slowing, or interference, in the HIV-negative group and two HIV-positive groups (unimpaired and impaired) was quite large (between 122 and 131 ms). We argue that the lack of such relative slowing in the most cognitively impaired HIV-positive group indicates a deficit in incidental learning and memory. |
| Databáze: | OpenAIRE |
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