Airway clearance and exercise for people with cystic fibrosis: Balancing longevity with life
| Autor: | T. Daniels, Nicola J. Rowbotham |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Airway clearance Cystic Fibrosis media_common.quotation_subject Longevity Cystic Fibrosis Transmembrane Conductance Regulator Cystic fibrosis medicine Humans Pediatrics Perinatology and Child Health Precision Medicine Intensive care medicine media_common Lung business.industry Treatment burden Infant Newborn respiratory system Precision medicine medicine.disease respiratory tract diseases Cftr mutation medicine.anatomical_structure Mutation Pediatrics Perinatology and Child Health business RM695-893 Cftr modulator |
| Zdroj: | Pediatric Pulmonology. 57 |
| ISSN: | 1099-0496 8755-6863 |
| Popis: | Airway clearance has been an integral part of cystic fibrosis (CF) care for almost as long as CF has been identified as a condition. From diagnosis as a neonate through to end-of-life care, airway clearance is an everyday aspect of life, adding a considerable treatment burden to the lives of people with CF. There are many different techniques used for airway clearance which have evolved over time with an aim to improve effectiveness, support adherence and, more recently, to consider the impact of burden. A popular thought is whether airway clearance could be replaced by exercise. With new precision therapies in the form of CFTR modulators available, the CF landscape is rapidly changing, raising the question of whether certain treatments are needed at all. Depending on factors such as CFTR mutation, age, and pre-existing lung damage before starting a CFTR modulator, individuals with CF may need different levels of intensity and type of maintenance treatment. Precision medicine is likely to lead to the need for increased precision and individualized management around other maintenance therapies such as airway clearance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text