Additional file 1 of Ethaselen synergizes with oxaliplatin in tumor growth inhibition by inducing ROS production and inhibiting TrxR1 activity in gastric cancer

Autor: Zhang, Haiyong, Wu, Jing, Yuan, Jinqiu, Li, Huafu, Zhang, Yawei, Wu, Wang, Chen, Wei, Wang, Chunming, Meng, Sijun, Chen, Songyao, Huo, Mingyu, He, Yulong, Zhang, Changhua
Rok vydání: 2021
DOI: 10.6084/m9.figshare.15567459.v1
Popis: Additional file 1: Figure S1. The planar structure of BBSKE. Figure S2. Effects of BBSKE on cellular proliferation. Figure S3. Pretreatment with GSH markedly attenuated the combined treatment-induced cell growth inhibition in gastric cancer cells. Figure S4. The inhibiting efficiencies of p-p38 and p-JNK by BMS-582949 and SP600125 respectively. Figure S5. Molecular docking of BBSKE with TrxR1 protein was carried out with the docking software. Figure S6. BBSKE reduced the toxicity of cisplatin in vivo. Figure S7. The morphology of 3 cases of successful established human gastric cancer organoids (hGCO1-3) under white field microscope.
Databáze: OpenAIRE