Organic electrochemical transistors as impedance biosensors

Autor:	Gregório Couto Faria, Róisín M. Owens, Duc T. Duong, Jonathan Rivnay, George G. Malliaras, Stergios Logothetidis, Christos A. Polyzoidis, Alberto Salleo
Rok vydání:	2014
Předmět:	Materials science Transistor technology industry and agriculture Nanotechnology macromolecular substances Diagnostic tools Electrochemistry law.invention Barrier layer Membrane law ELETROQUÍMICA ORGÂNICA General Materials Science Lipid bilayer Biosensor Electrical impedance
Zdroj:	Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP
ISSN:	2159-6867 2159-6859
Popis:	Interfacing organic electrochemical transistors (OECTs) with biological systems holds considerable promise for building-sensitive biosensors and diagnostic tools. We present a simple model that describes the performance of biosensors in which an OECT is integrated with a biological barrier layer. Using experimentally derived parameters we explore the limits of sensitivity and find that it is dependent on the resistance of the barrier layer. This work provides guidelines on how to optimize biosensors in which OECTs transduce changes in the impedance of biological layers, including lipid bilayer membranes and confluent cell layers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0442013ac077ba7dde515aacdb76741d https://doi.org/10.1557/mrc.2014.35 Zobrazit plný text záznamu Full text from SpringerLink