Intravitreal Diclofenac in the Treatment of Macular Edema Due to Branch Retinal Vein Occlusion
| Autor: | Usha K Raina, Basudeb Ghosh, Anisha Seth, Anika Gupta, Supriya Arora |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Intraocular pressure Diclofenac Visual acuity genetic structures Visual Acuity Macular Edema 03 medical and health sciences 0302 clinical medicine Ophthalmology Retinal Vein Occlusion medicine Humans Prospective Studies Fluorescein Angiography Prospective cohort study Macular edema Intraocular Pressure Aged Fundus fluorescein angiography medicine.diagnostic_test business.industry Anti-Inflammatory Agents Non-Steroidal Middle Aged medicine.disease Fluorescein angiography eye diseases Surgery Intravitreal Injections 030221 ophthalmology & optometry Branch retinal vein occlusion Female sense organs Ophthalmic Solutions medicine.symptom business Tomography Optical Coherence 030217 neurology & neurosurgery Follow-Up Studies medicine.drug |
| Zdroj: | Ophthalmic Surgery, Lasers and Imaging Retina. 47:149-155 |
| ISSN: | 2325-8179 2325-8160 |
| DOI: | 10.3928/23258160-20160126-08 |
| Popis: | BACKGROUND AND OBJECTIVE: To evaluate the effect of a single dose of intravitreal diclofenac on macular edema (ME) due to branch retinal vein occlusion (BRVO). PATIENTS AND METHODS: In this prospective, interventional case series, 15 eyes with BRVO and ME with central macular thickness (CMT) greater than 250 µm on spectral-domain optical coherence tomography (SD-OCT) were enrolled. All patients were given 0.05 mg/0.1 mL of intravitreal diclofenac under aseptic conditions and followed up for 3 months with respect to best-corrected visual acuity (BCVA), intraocular pressure (IOP), fundus fluorescein angiography, and CMT measured on OCT. RESULTS: The mean visual acuity improved from 0.115 ± 0.03 preoperatively to 0.356 ± 0.29 at 3 months ( P = .002). Mean line improvement was 2.2 ± 1.6. Mean preoperative CMT decreased from 453.2 µm ± 55.3 µm to 340.47 µm ± 101 µm at 3 months postoperatively ( P = .001). The mean preoperative IOP was 16.4 mm Hg ± 1.59 mm Hg, whereas the mean postoperative IOP was 16.6 mm Hg ± 1.58 mm Hg ( P = .08). None of the 12 phakic eyes showed evidence of cataract progression. CONCLUSION: Intravitreal diclofenac is safe and effective in improving BCVA and decreasing CMT in patients with BRVO and ME. [ Ophthalmic Surg Imaging Lasers Retina . 2016;47:149–155.] |
| Databáze: | OpenAIRE |
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