Influence of surface modifications on the degradation of standard-sized magnesium plates and healing of mandibular osteotomies in miniature pigs
| Autor: | Yahya Açil, T. Klüter, Hendrik Naujokat, J.-M. Seitz, Jörg Wiltfang, C.B. Ruff |
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| Rok vydání: | 2018 |
| Předmět: |
Biocompatibility
Swine medicine.medical_treatment Bone Screws Mandibular Osteotomy Bone healing Bone tissue Osteotomy 03 medical and health sciences 0302 clinical medicine Materials Testing Alloys Medicine Animals Magnesium Magnesium alloy Osteosynthesis business.industry Soft tissue 030206 dentistry X-Ray Microtomography medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Surface modification Swine Miniature Surgery Oral Surgery business Biomedical engineering |
| Zdroj: | International journal of oral and maxillofacial surgery. 49(2) |
| ISSN: | 1399-0020 |
| Popis: | Biodegradable magnesium alloys are suitable osteosynthesis materials. Despite the alloy composition, surface modifications appear to have an influence on the degradation process and biocompatibility. The aim of this study was to investigate the impact of hydrogenation and fluoridation of the surface in a mandibular osteotomy model. Standard-sized plates and screws were implanted in an osteotomy at the mandibular angle in nine miniature pigs. The plates and screws were harvested together with the adjacent tissues at 8 weeks after surgery and were investigated by micro-computed tomography and histological analysis. The bone healing of the osteotomy was undisturbed, independent of the surface properties. The adjacent bone tissue showed new bone formation at the implant surface; however, formation of some lacunae could be observed. The corrosion was between 9.8% and 11.6% (fluoridated |
| Databáze: | OpenAIRE |
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