Biospecimen Complexity and the Evolution of Biobanks
| Autor: | Lise Matzke, Victoria Hartman, Peter H. Watson |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Biomedical Research
Process (engineering) Computer science media_common.quotation_subject Medicine (miscellaneous) General Biochemistry Genetics and Molecular Biology Specimen Handling 03 medical and health sciences 0302 clinical medicine Humans Quality (business) Operational costs media_common Biological Specimen Banks 030219 obstetrics & reproductive medicine Publications 0402 animal and dairy science 04 agricultural and veterinary sciences Cell Biology General Medicine 040201 dairy & animal science Biobank Data science Scale (social sciences) Sustainability Journal Impact Factor |
| Zdroj: | Biopreservation and biobanking. 17(3) |
| ISSN: | 1947-5543 |
| Popis: | Biospecimens are critical in driving health research. There is increased demand for scale and quality of biospecimens that in turn drives biobanking operational costs, influences utilization, and threatens the sustainability of individual biobanks. Biospecimen research has begun to inform the details of new biobanking standards and the steps of the biobanking process that are most important to focus on to achieve higher quality. This focus on quality is currently centered mostly on intrinsic features of biospecimens and their annotating data. This review highlights additional quality features that are important to researchers in determining the fit for purpose in their research. First, we define complex qualities as those that are mostly extrinsic to the individual biospecimen and data, and second, we provide data on the growth in demand for biospecimens with this type of quality in cancer research biobanks. Finally, we discuss why biospecimen complexity is a challenge for biobanks and utilization of existing collections, and provide examples of strategies biobanks can consider to improve their focus on this aspect of quality, as we predict that researcher demand for complex biospecimens will continue to expand in the future. |
| Databáze: | OpenAIRE |
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