Fetal regional myocardial strain rate in the membranous ventricular septum: changes with gestational age and the left ventricular mass and predictive value for a complete membranous ventricular septum (without defect)
| Autor: | Ke-Qi Chen, Yun-Yan Shi, Li-Juan Zhang, Xiao-Zhi Zheng |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Heart Septal Defects
Ventricular medicine.medical_specialty Heart Ventricles 0206 medical engineering Gestational Age 02 engineering and technology Ventricular Septum 030204 cardiovascular system & hematology Ultrasonography Prenatal 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Pregnancy Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Interventricular septum Prospective Studies Fetus medicine.diagnostic_test Receiver operating characteristic business.industry Infant Newborn Gestational age medicine.disease 020601 biomedical engineering medicine.anatomical_structure Echocardiography Predictive value of tests Cardiology Gestation Female Cardiology and Cardiovascular Medicine business Fetal echocardiography |
| Zdroj: | The international journal of cardiovascular imaging. 34(9) |
| ISSN: | 1875-8312 |
| Popis: | To describe the fetal regional myocardial strain rate in the membranous ventricular septum across gestation and to determine their predictive value for a complete membranous ventricular septum (without defect) after delivery. In 1150 fetuses, the peak systolic strain rate (SRs), peak early diastolic strain rate (SRe) and peak late diastolic strain rate (SRa) in the membranous ventricular septum were measured at four time points across gestation (18-20, 24-26, 30-32 and 36-38 weeks). The integrity of the interventricular septum was examined at 12 weeks' postnatal age. The correlations between myocardial strain rates and gestational age as well as fetal left ventricular mass were analyzed, and the performance of myocardial strain rates in predicting a complete membranous ventricular septum was deducted. Strain rate absolute values in the membranous ventricular septum all increased across gestation. They all significantly correlated with gestational age and left ventricular mass. At 24 weeks during pregnancy, the areas under the receiver operating characteristics curve (AUC) for SRe and SRa were all > 0.72 (p 1.53 s-1) for SRe was 62.5, 85.7 and 73.3%, respectively, and the sensitivity, specificity and accuracy of the cut off value (> 1.51 s-1) for SRa was 75.2, 71.9 and 73.8%, respectively. The changes of myocardial strain rates in the membranous ventricular septum across gestation maybe can be used to predict a complete membranous ventricular septum after delivery. |
| Databáze: | OpenAIRE |
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