Nosocomial Respiratory Infections in a Rural Zambian Hospital

Autor: Richard E. Rothman, Kristina K Zudock, Lauren Sauer, Philip E. Thuma, Thomas Mehoke, Peter Thielen, Katherine Z.J. Fenstermacher, Jared D. Evans, Kathryn Shaw-Saliba, Justin Hardick, Mwaka Monze, Charlotte A. Gaydos, Gideon Loevinsohn, Catherine G. Sutcliffe, Kenneth V Bowden, Andrew Pekosz, Mutinta Hamahuwa, Pamela Sinywimaanzi
Rok vydání: 2021
Předmět:
Zdroj: Am J Trop Med Hyg
ISSN: 1476-1645
0002-9637
DOI: 10.4269/ajtmh.20-1470
Popis: The burden of nosocomial respiratory infections in rural southern Africa is poorly understood. We established a surveillance program at a rural Zambian hospital to detect influenza-like illness (ILI) and respiratory infections among hospitalized patients and a cohort of healthcare workers (HCWs). Nasopharyngeal specimens from symptomatic patients and HCWs underwent broadly multiplexed molecular testing to detect viruses and atypical bacteria. During 1 year of surveillance, 15 patients (1.7% of admissions) developed ILI more than 48 hours after admission. Among 44 HCWs, 19 (43%) experienced at least one ILI episode, with a total of 31 ILI episodes detected. Respiratory viruses were detected in 45% of patient and 55% of HCW specimens. The cumulative incidence of influenza infection among HCWs over 1 year was 9%. Overall, respiratory viruses were commonly found among patients and HCWs in a rural Zambian hospital with limited infection control infrastructure.
Databáze: OpenAIRE