Nosocomial Respiratory Infections in a Rural Zambian Hospital
Autor: | Richard E. Rothman, Kristina K Zudock, Lauren Sauer, Philip E. Thuma, Thomas Mehoke, Peter Thielen, Katherine Z.J. Fenstermacher, Jared D. Evans, Kathryn Shaw-Saliba, Justin Hardick, Mwaka Monze, Charlotte A. Gaydos, Gideon Loevinsohn, Catherine G. Sutcliffe, Kenneth V Bowden, Andrew Pekosz, Mutinta Hamahuwa, Pamela Sinywimaanzi |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male medicine.medical_specialty Rhinovirus Atypical bacteria Hospitalized patients Health Personnel Hospitals Rural education Zambia Infectious Disease Transmission Professional-to-Patient Cohort Studies Virology Internal medicine Influenza Human Patients' Rooms medicine Humans Infection control Cumulative incidence Prospective Studies Respiratory system Child Respiratory Tract Infections Cross Infection Infection Control Picornaviridae Infections business.industry virus diseases Articles Infectious Diseases Influenza Vaccines Child Preschool Cohort Female Parasitology business |
Zdroj: | Am J Trop Med Hyg |
ISSN: | 1476-1645 0002-9637 |
DOI: | 10.4269/ajtmh.20-1470 |
Popis: | The burden of nosocomial respiratory infections in rural southern Africa is poorly understood. We established a surveillance program at a rural Zambian hospital to detect influenza-like illness (ILI) and respiratory infections among hospitalized patients and a cohort of healthcare workers (HCWs). Nasopharyngeal specimens from symptomatic patients and HCWs underwent broadly multiplexed molecular testing to detect viruses and atypical bacteria. During 1 year of surveillance, 15 patients (1.7% of admissions) developed ILI more than 48 hours after admission. Among 44 HCWs, 19 (43%) experienced at least one ILI episode, with a total of 31 ILI episodes detected. Respiratory viruses were detected in 45% of patient and 55% of HCW specimens. The cumulative incidence of influenza infection among HCWs over 1 year was 9%. Overall, respiratory viruses were commonly found among patients and HCWs in a rural Zambian hospital with limited infection control infrastructure. |
Databáze: | OpenAIRE |
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