Social Cognition in Patients with Amnestic Mild Cognitive Impairment and Mild Dementia of the Alzheimer Type
| Autor: | Katrin Schuermann, Frank Jessen, Daniel Scharfenberg, Ann-Katrin Schild, Dix Meiberth, Oezguer A. Onur, Franziska Maier, Jenny Volk |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Social Cognition medicine.medical_specialty psychology [Dementia] Theory of Mind Audiology Neuropsychological Tests Social cognition Theory of mind emotion recognition mental disorders Medicine Dementia Humans In patient Cognitive Dysfunction ddc:610 Neuropsychological assessment complications [Dementia] Aged psychology [Amnesia] medicine.diagnostic_test business.industry General Neuroscience dementia of the Alzheimer type Cognition General Medicine medicine.disease Psychiatry and Mental health Clinical Psychology statistics & numerical data [Neuropsychological Tests] Amnestic mild cognitive impairment Female psychology [Cognitive Dysfunction] Amnesia Geriatrics and Gerontology complications [Cognitive Dysfunction] business Neurocognitive Facial Recognition Cognitive load |
| Zdroj: | Journal of Alzheimer's disease 83(3), 1173-1186 (2021). doi:10.3233/JAD-201126 |
| ISSN: | 1875-8908 |
| DOI: | 10.3233/JAD-201126 |
| Popis: | Background: Social cognition (SC) is a core criterion for neurocognitive disorders. However, findings in patients with amnestic mild cognitive impairment (aMCI) and dementia of the Alzheimer type (DAT) are inconsistent. Objective: We report assessments of emotion recognition (ER), affective and cognitive theory of mind (ToM) in young (YC) and older controls (OC) compared to aMCI and DAT. Methods: 28 aMCI, 30 DAT, 30 YC, and 29 OC received tests of SC and a comprehensive neuropsychological assessment. Analysis of covariance was used to determine group differences. Multiple regression models were applied to identify predictors for each SC task. Results: In controls, OC performed worse in ER and both ToM tasks compared to YC except for one subtest. No significant differences were found between OC and patients concerning ER and affective ToM. In cognitive ToM, differences between OC and patients depended on content and cognitive load with significant impairment in DAT compared to OC. A cognitive composite score predicted SC in OC, but not in patients. Associations of SC with single cognitive domains were found in all groups with language and complex attention as best predictors. Not all variance of SC performance was explained by variance in cognitive domains. Conclusion: Lower performance on SC tasks in OC versus YC was confirmed, although not all tasks were equally affected. With progressive cognitive impairment, cognitive ToM is more impaired than ER or affective ToM. SC seems to be at least partly independent of other cognitive domains, justifying its inclusion in batteries for dementia diagnostic. |
| Databáze: | OpenAIRE |
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