Phantom limb pain after unilateral arm amputation is associated with decreased heat pain thresholds in the face
| Autor: | Jamila Andoh, Herta Flor, Mariela Rance, Susanne Becker, Christopher Milde, Xaver Fuchs, Robin Bekrater-Bodmann, Jörg Trojan, Martin Diers, Pinar Kirsch, Jens Foell |
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| Přispěvatelé: | University of Zurich, Fuchs, Xaver |
| Rok vydání: | 2021 |
| Předmět: |
Pain Threshold
medicine.medical_specialty Hot Temperature chemical and pharmacologic phenomena Heat pain 610 Medicine & health Phantom limb pain Amputation Surgical Amputees immune system diseases Negatively associated Sensory threshold Internal medicine medicine Arm amputation Humans business.industry Quantitative sensory testing Chronic pain Small sample medicine.disease nervous system diseases body regions Anesthesiology and Pain Medicine Phantom Limb Cardiology Arm lipids (amino acids peptides and proteins) 10046 Balgrist University Hospital Swiss Spinal Cord Injury Center 2703 Anesthesiology and Pain Medicine business |
| Zdroj: | European journal of pain (London, England)REFERENCES. 26(1) |
| ISSN: | 1532-2149 |
| Popis: | BACKGROUND The mechanisms underlying chronic phantom limb pain (PLP) are complex and insufficiently understood. Altered sensory thresholds are often associated with chronic pain but quantitative sensory testing (QST) in PLP has so far been inconclusive due to large methodological variation between studies and small sample sizes. METHODS In this study, we applied QST in 37 unilateral upper-limb amputees (23 with and 14 without PLP) and 19 healthy controls. We assessed heat pain (HPT), pressure pain, warmth detection and two-point discrimination thresholds at the residual limb, a homologous point and the thenar of the intact limb as well as both corners of the mouth. RESULTS We did not find significant differences in any of the thresholds between the groups. However, PLP intensity was negatively associated with HPT at all measured body sites except for the residual limb, indicating lower pain thresholds with higher PLP levels. Correlations between HPT and PLP were strongest in the contralateral face (r = -0.65, p |
| Databáze: | OpenAIRE |
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