API-polymer interactions in Sepineo P600 based topical gel formulation- impact on rheology
Autor: | Abu Zayed Md Badruddoza, Thean Yeoh, Jaymin C. Shah |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | International Journal of Pharmaceutics. 621:121824 |
ISSN: | 0378-5173 |
DOI: | 10.1016/j.ijpharm.2022.121824 |
Popis: | In the present study, topical gel and emulsion gel were formulated using Acrylamide/ Sodium Acryloyldimethyl taurate copolymer (Sepineo P600) as a gelling agent, and their rheological attributes and physical stability were evaluated upon incorporation of API. Lidocaine, a free base drug (pK |
Databáze: | OpenAIRE |
Externí odkaz: |