First experience of comparisons between two different shear wave speed imaging systems in differentiating malignant from benign thyroid nodules
| Autor: | Xiao-Wan Bo, Hui-Xiong Xu, Chong-Ke Zhao, Xiao-Long Li, Wei-Wei Ren, Ya-Ping He, Dan Wang, Wen-Wen Yue, Bo-Ji Liu |
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| Rok vydání: | 2016 |
| Předmět: |
Thyroid nodules
Adult Male medicine.medical_specialty Physiology 030218 nuclear medicine & medical imaging 03 medical and health sciences Young Adult 0302 clinical medicine Physiology (medical) Biopsy medicine Humans Thyroid Nodule Aged Shear wave elastography Receiver operating characteristic medicine.diagnostic_test business.industry Ultrasound Reproducibility of Results Hematology Wave speed Middle Aged medicine.disease Predictive value Fine-needle aspiration 030220 oncology & carcinogenesis Elasticity Imaging Techniques Female Radiology Cardiology and Cardiovascular Medicine business Nuclear medicine |
| Zdroj: | Clinical hemorheology and microcirculation. 65(4) |
| ISSN: | 1875-8622 |
| Popis: | OBJECTIVE The purpose of this study was to comparatively evaluate the two different shear wave speed (SWS) imaging systems of Toshiba shear wave elastography (T-SWE) and SuperSonic SWE (S-SWE) in distinguishing malignant from benign thyroid nodules (TNs). MATERIALS AND METHODS 140 patients with 140 focal TNs were enrolled and underwent T-SWE and S-SWE before fine-needle aspiration (FNA) biopsy or surgery. SWE indices of mean, standard deviation and maximum values (E-mean, E-SD and E-max) of elastic modulus in TNs were measured on a color-coded mapping. The receiver operating characteristic (ROC) curve was performed to assess the diagnostic performance. RESULTS Of the 140 nodules, 47 were thyroid carcinomas and 93 were benign. Areas under the receiver operating characteristic curve (AUC) were the highest with E-max among the three SWE parameters both for T-SWE and S-SWE (0.816 and 0.799). The most accurate cut-off values, sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) were 26.6 kPa versus 42.9 kPa, 83.0% versus 63.8%, 68.8% versus 88.2%, 72.9% versus 80.0%, 56.5% versus 73.2% and 88.7% versus 82.8% with E-max for T-SWE and S-SWE, respectively. Among these comparisons, the sensitivity in T-SWE was statistically higher than S-SWE (83.0% versus 63.8%, p = 0.022), whereas specificity was statistically lower than S-SWE (68.8% versus 88.2%, p |
| Databáze: | OpenAIRE |
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