Magnetic field exposure of marrow donor mice can increase the number of spleen colonies (CFU-S 7d) in marrow recipient mice
| Autor: | H.-P. Peterson, K. H. von Wangenheim, L. E. Feinendegen |
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| Rok vydání: | 1992 |
| Předmět: |
Male
Pathology medicine.medical_specialty Time Factors Biophysics Spleen Mice Inbred Strains Biology Body Temperature Andrology Colony-Forming Units Assay Magnetics Mice medicine Animals Receptor General Environmental Science Bone Marrow Transplantation Radiation Magnetic field exposure Tissue Donors Transplantation Mice Inbred C57BL medicine.anatomical_structure Female Bone marrow Stem cell |
| Zdroj: | Radiation and environmental biophysics. 31(1) |
| ISSN: | 0301-634X |
| Popis: | Transplantation of bone marrow cells of magnetic-field-exposed mice led to increased numbers of spleen colonies (CFU-S 7d) in conditioned recipient mice (Peterson et al. 1986). Here we report on the dependence of this phenomenon on body temperature, field strength and exposure time. It was found that the effect can only be seen when the body temperature is 27 degrees C, the field strength not less than 1.4 T and the exposure time at least 15 min. It is suggested that the magnetic field increases the number of spleen colonies either directly by affecting membrane components (receptors) responsible for the seeding of the transplanted stem cells to the recipient spleens or indirectly affecting radical/redox-systems that may have a regulatory function in the stem cells. |
| Databáze: | OpenAIRE |
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