SUPERSATURATION AND STONE COMPOSITION IN A NETWORK OF DISPERSED TREATMENT SITES

Autor:	H. Mardis, James E. Lingeman, Michael Grasso, David S. Goldfarb, John R. Asplin, R. Kahnoski, S. Lacey, Fredric L. Coe, J.H. Parks
Rok vydání:	1998
Předmět:	Supersaturation Chromatography business.industry Urology Calcium oxalate chemistry.chemical_element Urine Calcium Oxalate Urine collection device chemistry.chemical_compound chemistry Biochemistry Medicine Uric acid Brushite business
Zdroj:	Journal of Urology. 159:1821-1825
ISSN:	1527-3792 0022-5347
DOI:	10.1016/s0022-5347(01)63164-1
Popis:	Purpose: We determined the validity of urine supersaturation assessed from 2, 24-hour urine collections from outpatients eating uncontrolled diets and receiving care at a network of treatment sites that uses a central laboratory. We compared supersaturation to stone composition to determine whether supersaturation values correlate with composition.Materials and Methods: Two 24-hour urine samples collected from 183 patients at 6 treatment sites were shipped to a single central laboratory. Complexations and crystallizations in vitro from aging during the transport step were interrupted by pH change in acid and alkaline directions. Relevant analytes were measured, and supersaturation was calculated for calcium oxalate, calcium phosphate as brushite and uric acid. Stone analysis was done at various laboratories.Results: Urine supersaturation values correlated well with stone composition. Higher calcium phosphate and uric acid supersaturation was noted when stones contained higher amounts of calcium ph...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040f0ed72a190eb3ecf3f2bc8a4fc26e https://doi.org/10.1016/s0022-5347(01)63164-1 Zobrazit plný text záznamu