Progress and prospects: gene therapy clinical trials (part 1)
| Autor: | B L, Alexander, R R, Ali, E W F, Alton, J W, Bainbridge, S, Braun, S H, Cheng, T R, Flotte, H B, Gaspar, M, Grez, U, Griesenbach, M G, Kaplitt, M G, Ott, R, Seger, M, Simons, A J, Thrasher, A Z, Thrasher, S, Ylä-Herttuala |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Cystic Fibrosis Eye Diseases Duchenne muscular dystrophy Genetic enhancement Coronary Disease Gene delivery Granulomatous Disease Chronic law.invention Randomized controlled trial law alpha 1-Antitrypsin Deficiency Genetics Medicine Humans Muscular dystrophy Intensive care medicine Molecular Biology Peripheral Vascular Diseases Severe combined immunodeficiency Clinical Trials as Topic business.industry Cancer Parkinson Disease Genetic Therapy medicine.disease Clinical trial Lysosomal Storage Diseases Muscular Dystrophy Duchenne Immunology Molecular Medicine Severe Combined Immunodeficiency business |
| Zdroj: | Gene therapy. 14(20) |
| ISSN: | 0969-7128 |
| Popis: | Over the last two decades gene therapy has moved from preclinical to clinical studies for many diseases ranging from single gene disorders such as cystic fibrosis and Duchenne muscular dystrophy, to more complex diseases such as cancer and cardiovascular disorders. Gene therapy for severe combined immunodeficiency (SCID) is the most significant success story to date, but progress in many other areas has been significant. We asked 20 leaders in the field succinctly to summarize and comment on clinical gene therapy research in their respective areas of expertise and these are published in two parts in the Progress and Prospect series. |
| Databáze: | OpenAIRE |
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