Reduced plasma carotenoids in individuals suffering from metabolic diseases with disturbances in lipid metabolism: a systematic review and meta-analysis of observational studies
| Autor: | Inês Mendes, Georg Lietz, Wasim A Iqbal, Kieran Finney, Anthony Oxley |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Physiology 030209 endocrinology & metabolism Overweight 03 medical and health sciences 0302 clinical medicine Metabolic Diseases Humans Medicine Obesity Vitamin A Carotenoid chemistry.chemical_classification 030109 nutrition & dietetics business.industry Dietary intake Lipid metabolism Non-communicable disease Lipid Metabolism medicine.disease Carotenoids Observational Studies as Topic chemistry Meta-analysis Observational study medicine.symptom business Food Science |
| Zdroj: | International Journal of Food Sciences and Nutrition. 72:879-891 |
| ISSN: | 1465-3478 0963-7486 |
| DOI: | 10.1080/09637486.2021.1882962 |
| Popis: | This review summarises the association between serum carotenoids, serum retinoids and dietary intake outcomes with obesity/overweight and individuals with metabolic diseases with disturbances in lipid metabolism. Observational studies reporting dietary intakes and serum concentrations of carotenoids and retinol were collected from Medline and Web of Science. Mean differences were calculated between “cases” (classified as obese, overweight or having a metabolic disease with disturbances in lipid metabolism; i.e. non-alcoholic fatty liver disease, type 2 diabetes, dyslipidaemia or metabolic syndrome) and “comparator group” (classified as normal weight healthy individuals) and summarised in meta-analyses. Significant summary measures were observed for most serum provitamin A and non-provitamin A carotenoids. Studies reporting total serum carotenoids had shown the greatest decrease (–0.28 µmol/l [–0.33, −0.23], pI2=62.5%, n = 7). There were no significant summary measures for dietary outcomes, suggesting a physiological role of low serum carotenoids in the development of obesity and associated diseases. |
| Databáze: | OpenAIRE |
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