Importance of the heart vector origin point definition for an ECG analysis: The Atherosclerosis Risk in Communities (ARIC) study
| Autor: | Larisa G. Tereshchenko, Aron Bender, Yin Li-Pershing, Kyle Johnson, Christopher Hamilton, Erick A. Perez-Alday, Kelley Newton, Jason Thomas, Aaron Li, Ryan Gonzales, Tiffany L. Lee |
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| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Vectorcardiography Beat (acoustics) Health Informatics Article Sudden cardiac death 03 medical and health sciences QRS complex 0302 clinical medicine Internal medicine medicine Humans Aric study medicine.diagnostic_test business.industry Signal Processing Computer-Assisted Middle Aged Atherosclerosis medicine.disease Computer Science Applications Atherosclerosis Risk in Communities Death Sudden Cardiac 030104 developmental biology cardiovascular system Cardiology Female business Electrocardiography Algorithms 030217 neurology & neurosurgery Kappa Follow-Up Studies |
| Zdroj: | Computers in Biology and Medicine. 104:127-138 |
| ISSN: | 0010-4825 |
| Popis: | AIM: —Our goal was to investigate the effect of a global XYZ median beat construction and the heart vector origin point definition on predictive accuracy of ECG biomarkers of sudden cardiac death (SCD). METHODS: —Atherosclerosis Risk In Community study participants with analyzable digital ECGs were included (n=15,768; 55% female, 73% white, mean age 54.2±5.8 y). We developed an algorithm to automatically detect the heart vector origin point on a median beat. Three different approaches to construct a global XYZ beat and two methods to locate origin point were compared. Global electrical heterogeneity was measured by sum absolute QRST integral (SAI QRST), spatial QRS-T angle, and spatial ventricular gradient (SVG) magnitude, azimuth, and elevation. Adjudicated SCD served as the primary outcome. RESULTS: —There was high intra-observer (kappa 0.972) and inter-observer (kappa 0.984) agreement in a heart vector origin definition between an automated algorithm and a human. QRS was wider in a median beat that was constructed using R-peak alignment than in time-coherent beat (88.1±16.7 vs. 83.7±15.9 ms; P |
| Databáze: | OpenAIRE |
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