The effects of hormone implants on serum lipoproteins and steroid hormones in bilaterally oophorectomised women
| Autor: | E. Farish, H. I. Abdalla, F A Azzawi, David M. Hart, C.D. Fletcher, Christina E. Gray |
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| Rok vydání: | 1984 |
| Předmět: |
Adult
medicine.medical_specialty Libido Lipoproteins Endocrinology Diabetes and Metabolism Lipoproteins VLDL chemistry.chemical_compound Endocrinology High-density lipoprotein Internal medicine medicine Humans Testosterone Castration skin and connective tissue diseases Drug Implants Estradiol business.industry Cholesterol General Medicine Sex hormone receptor Middle Aged medicine.disease Lipoproteins LDL Menopause chemistry Low-density lipoprotein Female lipids (amino acids peptides and proteins) Implant Lipoproteins HDL business Hormone |
| Zdroj: | Acta Endocrinologica. 106:116-120 |
| ISSN: | 1479-683X 0804-4643 |
| Popis: | Serum lipoproteins were measured over a period of 6 months in 14 oophorectomised women treated with oestrogen implants (50 mg oestradiol-17β) and 17 oophorectomised women treated with oestrogen/testosterone implants (50 mg oestradiol-17β, 100 mg testosterone). Both types of implant caused only minimal changes in lipoprotein metabolism. Low density lipoprotein (LDL) cholesterol decreased with both types of implant and high density lipoprotein (HDL) cholesterol rose with the oestrogen implants. HDL subfractions were also measured. The oestrogen implants caused a transient rise in HDL2 cholesterol levels at 2 months and a slower rise in HDL3 cholesterol. The oestrogen/testosterone implants had no effect on HDL fractions. The results indicate that hormone implants do not cause the profound changes in lipoproteins associated with oral hormone therapy. |
| Databáze: | OpenAIRE |
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