Prognostic criteria in colorectal carcinoma constructed by the combination of tumor-related and host-related factors
| Autor: | Rumi Matono, Hideki Ijichi, Takahiro Ezaki, Takefumi Ohga, Tadahiro Nozoe |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Oncology Curative resection medicine.medical_specialty Multivariate analysis Colorectal cancer Lymph node metastasis Adenocarcinoma Internal medicine Biomarkers Tumor medicine Histologic type Humans Aged Aged 80 and over Related factors biology business.industry C-reactive protein Significant difference General Medicine Middle Aged Prognosis medicine.disease Adenocarcinoma Mucinous Survival Analysis C-Reactive Protein Lymphatic Metastasis Multivariate Analysis biology.protein Female Surgery Colorectal Neoplasms business Follow-Up Studies |
| Zdroj: | The American Journal of Surgery. 208:119-123 |
| ISSN: | 0002-9610 |
| Popis: | BACKGROUND: The significance of prognostic criteria based on a combination of tumor-related and host-related factors for patients with colorectal carcinoma has not been appreciated fully. METHODS: Correlation of tumor-related and host-related score (TRHRS), which are constructed by the combination of serum elevation of C-reactive protein and pathologic lymph node metastasis (scores ranging 0 to 2), with clinicopathologic features including prognosis was studied in 271 patients with colorectal carcinoma who had been treated with curative resection. RESULTS: Significant difference regarding survival was observed both between TRHRS 0 and 1 (P 5.028) and between TRHRS 1 and 2 (P ,.0001). Multivariate analysis showed that histologic types (P 5 .040) and TRHRS (P , .0001) were independent prognostic indicators. CONCLUSION: Criteria for the prediction of prognosis in colorectal carcinoma treated with curative resection based on both tumor-related and host-related factors could provide a strict stratification. |
| Databáze: | OpenAIRE |
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