Hepatic Venous Pressure Gradients Measured by Duplex Ultrasound

Autor: V Kuoch, Laurence Rocher, Catherine Buffet, M. Blery, G PEletier, A. Miquel, J P Tasu, E Kulh
Rok vydání: 2002
Předmět:
Zdroj: Clinical Radiology. 57:746-752
ISSN: 0009-9260
DOI: 10.1053/crad.2002.0951
Popis: AIMS: The hepatic venous pressure gradient is a major prognostic factor in portal hypertension but its measurement is complex and requires invasive angiography. This study investigated the relationship between the hepatic venous pressure gradient and a number of Doppler measurements, including the arterial acceleration index. METHOD: We measured the hepatic venous pressure gradient in 50 fasting patients at hepatic venography. Immediately afterwards, a duplex sonographic examination of the liver was performed at which multiple measurements and indices of the venous and arterial hepatic vasculature were made. RESULTS: Hepatic arterial acceleration was correlated directly with the hepatic venous pressure gradient ( r = 0.83, P 0.0001) and with the Child–Pugh score ( r = 0.63, P 0.0001). An acceleration index cut-off value of 1m.s −2 provided a positive predictive value of 95%, a sensitivity of 65% and a specificity of 95% for detecting patients with severe portal hypertension (hepatic venous pressure gradient>12mmHg). A correlation between the hepatic venous pressure gradient and the congestion index of the portal vein velocity ( r = 0.45,P = 0.01) and portal vein velocity ( r = 0.40, P = 0.044), was also noted. CONCLUSION: Measuring the hepatic arterial acceleration index may help in the non-invasive evaluation of portal hypertension . Tasu, J-P. etal . (2002). Clinical Radiology 57 , 746–752.
Databáze: OpenAIRE