Paranasal sinus disease could be a reason for unsuccessful immunotherapy of inhalant allergy in children
| Autor: | Aleksandra Marciniak, Grażyna Mielnik-Niedzielska, Anna Horaczyńska-Wojtaś |
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| Rok vydání: | 2020 |
| Předmět: |
Allergen immunotherapy
medicine.medical_specialty medicine.medical_treatment Paranasal Sinuses otorhinolaryngologic diseases medicine Hypersensitivity Paranasal Sinus Diseases Humans Treatment Failure Sinusitis Child Pathological Nose Desensitization (medicine) Retrospective Studies business.industry Medical record Allergens medicine.disease Dermatology Paranasal sinuses medicine.anatomical_structure Otorhinolaryngology Desensitization Immunologic Immunotherapy business Tomography X-Ray Computed |
| Zdroj: | American journal of otolaryngology. 41(4) |
| ISSN: | 1532-818X |
| Popis: | Purpose The aim of this study was to evaluate the role of paranasal sinuses condition assessed in computed tomography on inhalant allergen desensitization effects. Materials & methods Retrospective analysis of medical records of children undergoing allergen immunotherapy in outpatient otolaryngology clinic of University Children Hospital in Lublin was performed. Control group consisted of children who underwent allergen immunotherapy and obtained satisfying effects; study group consisted of children who did not experience significant improvement after desensitization therapy. Results Computed tomography of nose cavity and paranasal sinuses exposed numerous pathologic changes affecting both, control and study group. Blockage of ostiomeatal complex was twice more common in children who did not respond adequately to desensitization therapy. In our study group, radiological findings suggesting rhinosinusitis were found in 73% of patients, while retention cysts in maxillary sinuses were discovered in 27% of patients. Conclusions Pathological findings in paranasal sinuses in computed tomography may arise from uncontrolled allergic rhinitis. If chirurgical management is indicated, allergen immunotherapy should be postponed until total recovery from operational procedure and repeated. |
| Databáze: | OpenAIRE |
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