Fatty acid components in Asian female patients with irritable bowel syndrome
| Autor: | Chian Sem Chua, Chyi Huey Bai, Chiao Wen Cheng, Chien-Yeh Hsu, Jung-Lung Hsu, Hung Wen Chiu, Shih Yi Huang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty Abdominal pain eicosapentaenoic acid Erythrocytes Observational Study Gastroenterology Fatty Acids Monounsaturated 03 medical and health sciences Young Adult 0302 clinical medicine Essential fatty acid Asian People Internal medicine Fatty Acids Omega-3 Medicine essential fatty acid Humans Body Weights and Measures Irritable bowel syndrome Depression (differential diagnoses) chemistry.chemical_classification irritable bowel syndrome Fatty Acids Essential business.industry Depression Fatty Acids Fatty acid General Medicine docosahexaenoic acid Middle Aged medicine.disease Eicosapentaenoic acid Abdominal Pain chemistry Docosahexaenoic acid Fatty Acids Unsaturated 030211 gastroenterology & hepatology Female medicine.symptom business 030217 neurology & neurosurgery Polyunsaturated fatty acid Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Abdominal pain is one of the key symptoms of irritable bowel syndrome (IBS). Studies have indicated an increase in the incidence of IBS in Asia. However, yet the pathophysiology of this disease remains unknown. Women are more likely to develop the condition than men, especially the constipation-predominant type. Essential fatty acid (EFA) malnutrition is one of several theories discussing the mechanism of IBS. The authors hypothesized that significant EFA deficiency may cause abdominal pain in patients with IBS. However, because patterns in the oral intake of EFAs differ between cultures, the authors narrowed this study to examine the nutritional status of Asian female patients with IBS The authors investigated Asian female patients with IBS and compared them with a group of healthy controls. Thirty patients with IBS and 39 healthy individuals were included in this study. The participants’ age, height, weight, and waist size were recorded. The 24-item Hamilton Depression Rating Scale was documented. Both erythrocyte and plasma fatty acid content were analyzed through gas–liquid chromatography. The authors found that patients with IBS exhibited significantly higher scores for depression, higher proportions of plasma saturated fatty acids and monounsaturated fatty acids, and lower proportions of docosahexaenoic acid and total omega-3 polyunsaturated fatty acids in plasma are associated with IBS in Asian female patients. Further study is indicated to confirm the causality of this association. |
| Databáze: | OpenAIRE |
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