Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications
| Autor: | Vilém Neděla, Peter Gemeiner, Marion B. Ansorge-Schumacher, Milan Polakovič, Juraj Svitel, Jaroslav Filip, Marek Bučko |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
System development Chemical reaction engineering 010405 organic chemistry Chemistry Bioengineering General Medicine Cells Immobilized equipment and supplies 01 natural sciences Applied Microbiology and Biotechnology 0104 chemical sciences 03 medical and health sciences Bioreactors 030104 developmental biology Biocatalysis Process economics Animals Humans Biochemical engineering Biotechnology |
| Zdroj: | Biotechnology Letters. 39:667-683 |
| ISSN: | 1573-6776 0141-5492 |
| DOI: | 10.1007/s10529-017-2300-y |
| Popis: | Viable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications. |
| Databáze: | OpenAIRE |
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