Pelvic organ prolapse surgery after native tissue vault suspension at hysterectomy-A prospective cohort study
| Autor: | Bent Ottesen, Lauge Østergaard, Lars Alling Møller, Helga Gimbel, Gunnar Gislason, Lisbeth Bonde, Emil L. Fosbøl |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Databases Factual medicine.medical_treatment Pelvic Organ Prolapse/prevention & control Hysterectomy Pelvic Organ Prolapse 03 medical and health sciences 0302 clinical medicine Risk Factors Suspension Medicine Humans Hysterectomy/methods Cumulative incidence 030212 general & internal medicine Prospective Studies Registries Prospective cohort study Pelvic organ 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Prolapse surgery Obstetrics and Gynecology Middle Aged Vaginal vault Surgery Pelvic organ prolapse Reproductive Medicine Hysteroscopy Native tissue Female business Benign indication |
| Zdroj: | Bonde, L, Østergaard, L, Fosbøl, E L, Møller, L A, Ottesen, B, Gislason, G H & Gimbel, H 2019, ' Pelvic organ prolapse surgery after native tissue vault suspension at hysterectomy-A prospective cohort study ', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 240, pp. 144-150 . https://doi.org/10.1016/j.ejogrb.2019.06.025 |
| DOI: | 10.1016/j.ejogrb.2019.06.025 |
| Popis: | OBJECTIVE: The effect of prophylactic vaginal vault suspension during hysterectomy in prevention of subsequent development of pelvic organ prolapse (POP) is unknown. We aimed to investigate incidences and risk of POP surgery in women who had undergone hysterectomy on benign indication with and without prophylactic suspension.STUDY DESIGN: We linked the national clinical Danish Hysterectomy and Hysteroscopy Database (DHHD) to administrative registries to assess data on all total hysterectomies (1 May 2012 to 31 December 2014), suspension methods, age, POP surgery, births, obstetric complications, prescriptions, socioeconomic- and vital status. Women undergoing total hysterectomy on non-prolapse and benign indication with no prior POP surgery were included and followed from hysterectomy to POP surgery, death/emigration or end of study period (maximum 2 years). Descriptive statistics, cumulative incidence curves and multivariable Cox proportional hazard models were fitted to assess the associated risk of POP in relation to prophylactic suspension.RESULTS: We included 7625 patients undergoing total hysterectomy; of these, 6538 (85.7%) were registered with prophylactic suspension during hysterectomy and 1087 (14.3%) women were specifically registered with no suspension in the DHHD. At baseline, women undergoing hysterectomy with suspension were on average 47.1 years of age (standard error SE 0.1) compared to 48.4 years (SE 0.3) in women with no suspension (p-value CONCLUSION: Of all women undergoing hysterectomy for benign indication, 0.84% (N = 64) were surgically treated for POP. At two-year follow-up, there was no association between prophylactic vaginal vault suspension at time of hysterectomy and subsequent POP surgery. |
| Databáze: | OpenAIRE |
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