Supplementary Materials and Methods, Figures S1 - S4 from Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma

Autor: Dieter Lemke, Wolfgang Wick, Harald Fricke, Michael Platten, Michael Kluge, Martin Bendszus, Claudia Kunz, Christian Gieffers, Jürgen Debus, Amir Abdollahi, Uwe Haberkorn, Manfred Jugold, Christian Merz, Benedikt Wiestler, Andreas von Deimling, Jaromir Sykora, Torsten Schmenger, Theresa Bunse, Antje Wick, Felix Sahm, Petra Rübmann, Philipp-Niclas Pfenning, Carina M. Thomé, Jonas Blaes
Rok vydání: 2023
DOI: 10.1158/1541-7786.22513288
Popis: Supplementary Figure 1: Detection of asunercept/ APG101 in brains of treated mice. Supplementary Figure 2: qPCR for MMP2 (A) or MMP9 (B) and representative images of human microglia after 12 h treatment with vehicle (I), 20 µg/ml APG101 (II), 50 U/ml CD95L (III) and both 20 µg/ml APG101 and 50 U/ml CD95L (IV). Supplementary Figure 3: APG101 is effective in murine cells. Supplementary Figure 4: Radiation effects on CD95L expression.
Databáze: OpenAIRE