Comparison of the Moskowitz criteria and the pouchitis disease activity index (PDAI) for diagnosis of ileoanal pouch inflammation

Autor:	D. W. Hamer-Hodges, Subrata Ghosh, D. C. C. Bartolo, N. Evgenikos
Rok vydání:	2001
Předmět:	medicine.medical_specialty medicine.diagnostic_test business.industry Gastroenterology Pouchitis medicine.disease Ulcerative colitis Neutrophilia Disease activity Internal medicine Biopsy medicine Pouch medicine.symptom Ileoanal pouch business Pouchoscopy
Zdroj:	Colorectal Disease. 3:161-164
ISSN:	1463-1318 1462-8910
DOI:	10.1046/j.1463-1318.2001.00211.x
Popis:	Objective To prospectively compare two indices for diagnosis of pouchitis: Moskowitz criteria and pouchitis disease activity index (PDAI). Patients and methods Fifty-six consecutive patients with an ileoanal pouch for ulcerative colitis were recruited. A clinical questionnaire was composed and the Oresland functional score calculated. Pouchoscopy and biopsy were performed after cleansing of the pouch. Results Seven patients had pouchitis according to both Moskowitz and PDAI (‘positive’ group). Five patients had PDAI ≥ 7, but did not fulfil the Moskowitz criteria (‘negative’ group). The pouchoscopy and Oresland functional scores were similar between the two groups. The biopsy neutrophilia and ulceration were more prominent in the ‘positive’ group (χ2=5.18, P
Databáze:	OpenAIRE
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