Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17

Autor:	Madhu Gupta, Kawaljeet Singh Sandha, R.K. Jain, M D Abu Bashar, Shuchi Aggarwal, Sunil Kumar, Sathiabalan Murugan, Krishna Chaudhary, Ankita Kankaria, Chering Bhag
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	medicine.medical_specialty viruses Population Attack rate lcsh:Medicine 030209 endocrinology & metabolism Context (language use) jaundice 03 medical and health sciences 0302 clinical medicine Environmental health Epidemiology Medicine hepatitis e 030212 general & internal medicine education hepatitis a attack rate education.field_of_study business.industry lcsh:R Outbreak Hepatitis A medicine.disease Hepatitis E outbreak investigation Original Article business Viral hepatitis
Zdroj:	Journal of Family Medicine and Primary Care, Vol 9, Iss 4, Pp 1856-1867 (2020) Journal of Family Medicine and Primary Care
ISSN:	2249-4863
Popis:	Context: During ongoing passive surveillance in Burail, Chandigarh an unexpected rise in number of acute viral hepatitis (AVH) was reported during December 2016. Aims: An outbreak of AVH was investigated in an urbanized village, Burail, in Chandigarh, India with an objective of describing its epidemiological features. Settings and Design: A house-to-house survey was conducted in Burail (population 51,958). Subjects and Methods: WHO's standard case definition for AVH was used to identify cases. Suspected cases were tested for hepatitis A virus (HAV) and E virus (HEV) using enzyme-linked immunosorbent assay. Drinking water samples were tested for fecal contamination. Control measures were implemented to contain the outbreak. Statistical Analysis Used: Descriptive analysis was done as per time, person, and place. Results: Out of 141 confirmed cases of AVH, 85.1% were positive for HEV, 12.8% for HAV, and 2.1% for both HAV and HEV. The attack rate was 27.1 per 10,000 in a population. Males were affected more than females (P < 0.05). One of the areas reported a leakage in drinking water pipeline and had highest attack rate (36.8/10000 population). Drinking water samples were found negative for contamination. Around 27% of confirmed cases reported history of taking food from local vendors in Burail 2–6 weeks prior to the onset of symptoms. Conclusion: This study described the epidemiological features of dual hepatitis outbreak due to HAV and HEV from Chandigarh, Union Territory, north India.
Databáze:	OpenAIRE
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