Successful Treatment of Severe Orthostatic Hypotension with Erythropoietin
| Autor: | Kazunobu Kawakami, Nobuya Harayama, Yasuhide Nakashima, Haruhiko Abe |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Supine position Anemia Fludrocortisone Blood Pressure Syncope Blood pressure drop Hypotension Orthostatic Tilt table test Orthostatic vital signs Tilt-Table Test Humans Medicine Erythropoietin Aged Amyloid Neuropathies Familial Presyncope medicine.diagnostic_test business.industry General Medicine medicine.disease Recombinant Proteins Anesthesia Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Pacing and Clinical Electrophysiology. 26:105-107 |
| ISSN: | 1540-8159 0147-8389 |
| DOI: | 10.1046/j.1460-9592.2003.00158.x |
| Popis: | A 71-year-old man, who was diagnosed with familial amyloidosis type I, was admitted for treatment of severe orthostatic hypotension associated with recurrent syncopal attacks. Head-up tilt testing demonstrated severe orthostatic hypotension (114/72 mmHg in the supine position and 62/34 mmHg in the upright position) with syncope or presyncope. Oral midodorine and fludrocortisone therapies failed to prevent his symptoms. After administration of subcutaneous erythropoietin, his blood pressure drop in the upright position was decreased and symptoms disappeared unassociated with improvement of anemia. Although previous reports have shown that the mechanism by which erythropoietin improves orthostatic hypotension is related to improvement in anemia, other mechanisms may also play a role. |
| Databáze: | OpenAIRE |
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